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Skin Grafts for Diabetic Ulcers: Why I Use Amnion

When a Wound Won't Close

Sometimes a wound just does not want to close. That is when I consider using a skin substitute or graft.
But I do not take skin from your thigh. I use amnion. It is a special material made from placenta tissue. It has growth factors, it is sterile, and it helps wounds close faster.

Why I Do Not Use Skin from Your Thigh

If I take a graft from your thigh, I am just creating another wound to try and close the first one.
That is especially risky if your healing is already slow.
Now you have two wounds instead of one.
That is why I use engineered tissue. I use amnion.

What Amnion Does

Amnion comes from placental tissue. It is full of natural growth signals.
I place it over the wound once the surface is clean and ready. Then we cover it with special dressings and remove pressure from the foot.
The purpose is to help your body build new skin.
It does not just cover the area. It tells the body it is time to heal.

Not Every Wound Qualifies

I do not use amnion on infected wounds.
First I have to treat the infection, improve blood flow, and get the wound healthy.
Once that happens, the graft has a better chance of working.
This is not a shortcut. It is a part of the process. It supports what the body is already doing.

Final Thought

Patients ask me if it is worth it. I tell them this:
If your wound is clean, and we have taken care of everything else, then yes — this can help.
We do not use it on everyone. But when the time is right, it helps move the healing forward.

Written by Dr. John Marzano

Board-certified podiatric surgeon with 35+ years of experience in wound care